The NRI partners used all the resources provided by the explicit funding to maintain and upgrade some of their equipment, improve their user support functionality and purchase new state-of-the-art systems and software in the imaging field. More importantly, the NRI partners established a high-standard research network in the field of imaging.

Μore than 60 publications have been extracted from the research activities held in the Bioimaging NRI, while below you can see some of the most important ones:

  1. Papathanasiou M., Tsiftsoglou S.A., Polyzos A.P., Papadopoulou D., Valakos D., Klagkou E., Karagianni P., Pliatska M., Talianidis I., Agelopoulos M., Thanos D. (2021) Identification of a dynamic gene regulatory network required for pluripotency factor-induced reprogramming of mouse fibroblasts and hepatocytes. The EMBO Journal, 40(1):e102236
  2. GJ Tserevelakis, KG Mavrakis, N Kakakios, G Zacharakis. (2021) Full image reconstruction in frequency-domain photoacoustic microscopy by means of a low-cost I/Q demodulator. Optics Letters 46 (19), 4718-4721
  3. M Orfanakis, GJ Tserevelakis, G Zacharakis. (2021) A Cost-Efficient Multiwavelength LED-Based System for Quantitative Photoacoustic Measurements. Sensors 21 (14), 4888
  4. Maria Tampakaki, Mariam-Eleni Oraiopoulou, Eleftheria Tzamali, Giorgos Tzedakis, Takis Makatounakis, Giannis Zacharakis, Joseph Papamatheakis, Vangelis Sakkalis. (2021) PML Differentially Regulates Growth and Invasion in Brain Cancer. International Journal of Molecular Sciences 22 (12), 6289
  5. Tserevelakis G.J., Pouli P., Zacharakis G. (2020) Listening to laser light interactions with objects of art: a novel photoacoustic approach for diagnosis and monitoring of laser cleaning interventions. Heritage Science, 8 (1), 1-13
  6. TserevelakisJ., Mavrakis K.G., Pantazopoulou D., Lagoudaki E., Detorakis E., and Zacharakis G. (2020)  Hybrid autofluorescence and photoacoustic label-free microscopy for the investigation and identification of malignancies in ocular biopsies Opt. Lett., 45, 5748-5751 
  7. Daskalaki I. and Tavernarakis N.(2020) Mitochondrial biogenesis in organismal senescence and neurodegeneration. Mechanisms of Ageing and Development, 191: 111345.
  8. Metaxakis A., Petratou D. and Tavernarakis N.(2020) Molecular interventions towards Multiple Sclerosis treatment. Brain Sciences, 10: e299.
  9. Markaki M. and Tavernarakis N.(2020) Mitochondrial turnover and homeostasis in ageing and neurodegeneration. FEBS Letters, 594: 2370-2379.
  10. Theodosiou T., Papanikolaou N., Savvaki M., Bonetto G., Maxouri S., Fakourelli E., Eliopoulos A. G., Tavernarakis N., Amoutzias G., Pavlopoulos G. A., Aivaliotis M., Nikoletopoulou V., Tzamarias D., Karagogeos D. and Iliopoulos I. (2020)UniProt Related Documents (UniReD): assisting wet lab biologists in their quest on finding novel counterparts in a protein network. Nucleic Acids Research - Genomics and Bioinformatics, 2: lqaa005.
  11. Markaki M. and Tavernarakis N.(2020) Caenorhabditis elegans as a model system for human diseases. Current Opinion in Biotechnology, 63: 118-125.
  12. Charmpilas C., Ruckenstuhl C., Sica V., Büttner S., Habernig L., Dichtinger S., Madeo F., Tavernarakis N., Bravo-San Pedro J.M. and Kroemer G. (2020)Acyl-CoA-binding protein (ACBP): a phylogenetically conserved appetite stimulator. Cell Death and Disease, 11: 7. 
  13. Panagiotaki K. N., Spyrou K., Zachariadis M., Pratsinis H., Kouloumpis A., Boutsika L. G., Enotiadis A., Gournis D., Giannelis E. P., Sideratou Z. (2020) Non-porous phosphonated ionic silica nanospheres as nanocarriers for efficient intracellular delivery of doxorubicin. Today Commun., 23: 100787
  14. Kazantzis K. T., Koutsonikoli K., Mavroidi B., Zachariadis M., Alexiou P., Pelecanou M., Politopoulos K., Alexandratou E., Sagnou M. (2020) Curcumin derivatives as photosensitizers in photodynamic therapy: photophysical properties and in vitro studies with prostate cancer cells. Photobiol. Sci., 19: 193–206
  15. Gkolfinopoulou C., Soukou F., Dafnis I., Kellici T. F., Sanoudou D., Mavromoustakos T., Stratikos E., Chroni A. (2020) Structure–function analysis of naturally occurring apolipoprotein A‑I L144R, A164S and L178P mutants provides insight on their role on HDL levels and cardiovascular risk. Mol. Life Sci., in press
  16. Sagnou M., Mavroidi B., Kaminari A., Boukos N., Pelecanou M. (2020) Novel Isatin Thiosemicarbazone Derivatives as Potent Inhibitors of β-Amyloid Peptide Aggregation and Toxicity. ACS Chem. Neurosci., 11: 2266–2276
  17. Prousis K.C., Canton-Vitoria R., Pagona R., Goulielmaki M., Zoumpourlis V., Tagmatarchis N., Calogeropoulou T. (2020) New cationic heptamethinecyanine-graphene hybrid materials. Dyes Pigm. 175, 108047
  18. Gavriil V., Chatzichristidi M., Christofilos D., Kourouklis G. A., Kollia Z., Bakalis E., Cefalas A.C. and Sarantopoulou E. (2020). Entropy and Random Walk Trails Water Confinement and Non-Thermal Equilibrium in Photon-Induced Nanocavities. Nanomaterials, 10(9), 1101
  19. Sarantopoulou E. (2020). Special Issue "Dynamics and Applications of Photon-Nanostructured Systems. Nanomaterials, 10(9), 1741
  20. Gkogkou E., Barnasas G., Vougas K., Trougakos I.P. (2020) Expression profiling meta-analysis of ACE2 and TMPRSS2, the putative anti-inflammatory receptor and priming protease of SARS-CoV-2 in human cells, and identification of putative modulators. Redox Biology, 36; 2020:101615,
  21. Panagopoulos A., Taraviras S., Nishitani H., Lygerou Z. (2020) CRL4Cdt2: Coupling Genome Stability to Ubiquitination. Trends Cell Biol., 30(4):290-302.
  22. Nathanailidou P., Taraviras S., Lygerou Z. (2020) Chromatin and Nuclear Architecture: Shaping Replication in 3D. Trends in Genetics, Dec;36(12):967-980.
  23. Kaltezioti V., Foskolou I.P., Lavigne M.D., Ninou E., Tsampoula M., Fousteri M., Margarity M., Politis P.K. (2020) Prox1 inhibits neurite outgrowth during central nervous system development. Cellular and Molecular Life Sciences, 78(7):3443-3465
  24. Peta C., Tsirimonaki E., Samouil D., Georgiadou K. and Mangoura D. (2020) Nuclear Isoforms of Neurofibromin Are Required for Proper Spindle Organization and Chromosome Segregation. Cells, 9(11):2348
  25. Kouroupi G., Antoniou N., Prodromidou K., Taoufik E., Matsas R. (2020). Patient-Derived Induced Pluripotent Stem Cell-Based Models in Parkinson's Disease for Drug Identification. Int J Mol Sci., 21(19): 7113.
  26. Zygogianni O., Kouroupi G., Taoufik E., Matsas R. (2020) Engraftable Induced Pluripotent Stem Cell-Derived Neural Precursors for Brain Repair. Methods Mol Biol., 2155: 23-39.
  27. Papadimitriou E., Koutsoudaki P.N., Karamitros T., Karagkouni D., Chroni-Tzartou D., Gkemisis C., Margariti M., Xingi E., Thanou I., Tzartos S.J., Hatzigeorgiou A.G., Thomaidou D. (2020) A miR-124-mediated post-transcriptional mechanism controlling the cell fate switch of astrocytes to induced-neurons. Cell Reports, (under revision).
  28. Daras G, Rigas S, Alatzas A, Samiotaki M, Chatzopoulos D, Tsitsekian D, Papadaki V, Templalexis D, Banilas G, Athanasiadou AM, Kostourou V, Panayotou G, Hatzopoulos P. (2019) LEFKOTHEA Regulates Nuclear and Chloroplast mRNA Splicing in Plants. Dev Cell., 50(6):767-779.e7.
  29. Kouroumalis A., Mavrogonatou E., Savvidou O. D., Papagelopoulos P.J., Pratsinis H., Kletsas D. (2019) Major traits of the senescent phenotype of nucleus pulposus intervertebral disc cells persist under the specific microenvironmental conditions of the tissue. Ageing Dev., 177:118-127
  30. Gumeni S., Evangelakou Z., Tsakiri E.N., Scorrano L., Trougakos I.P. (2019) Functional wiring of proteostatic and mitostatic modules ensures transient organismal survival during imbalanced mitochondrial dynamics. Redox Biol., 24:101219
  31. Tsakiri E.N., Gumeni S., Vougas K., Pendin D., Papassideri I., Daga A., Gorgoulis V., Juhász G., Scorrano L., Trougakos I.P. (2019) Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy. Autophagy, 15(10):1757-1773.
  32. Tsakiri E.N., Gumeni S., Iliaki K.K., Benaki D., Vougas K., Sykiotis G.P., Gorgoulis V.G., Mikros E., Scorrano L., Trougakos I.P. (2019) Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation. Aging Cell, 18(1): e12845.
  33. Efentakis P., Kremastiotis G., Varela A.., Nikolaou P.E., Papanagnou E.D., Davos C.H., Tsoumani M., Agrogiannis G., Konstantinidou A., Kastritis E., Kanaki Z., Iliodromitis E.K., Klinakis A., Dimopoulos M.A., Trougakos I.P., Andreadou I., Terpos E. (2019) Molecular mechanisms of carfilzomib-induced cardiotoxicity in mice and the emerging cardioprotective role of metformin. Blood, 133(7):710-723.
  34. Sarmento-Ribeiro A.B., Scorilas A., Gonçalves A.C., Efferth T., Trougakos I.P. (2019) The emergence of drug resistance to targeted cancer therapies: Clinical evidence. Drug Resist Updat., 47:100646.
  35. Alexa-Stratulat T., Pešić M., Gašparović A.Č., Trougakos I.P., Riganti C. (2019) What sustains the multidrug resistance phenotype beyond ABC efflux transporters? Looking beyond the tip of the iceberg. Drug Resist Updat., 46:100643.
  36. Manola M.S., Tsakiri E.N., Trougakos I.P. (2019) Alterations in Organismal Physiology, Impaired Stress Resistance, and Accelerated Aging in Drosophila Flies Adapted to Multigenerational Proteome Instability. Oxid Med Cell Longev., 2019:7823285.
  37. Vogiatzi A., Mavrothalassitis G. (2019) Craniofacial, orofacial and dental disorders: the role of the RAS/ERK pathway. Expert Rev Mol Med., 21: e2.
  38. Grigoriou M., Banos A., Filia A., et al. (2019) Transcriptome reprogramming and myeloid skewing in haematopoietic stem and progenitor cells in systemic lupus erythematosus. Ann Rheum Dis 0:1–12.
  39. Oraiopoulou M.E., Tzamali E., Tzedakis G., Liapis E., Zacharakis G., Vakis A., Papamatheakis J., Sakkalis V. (2018) Integrating in vitro experiments with in silico approaches for Glioblastoma invasion: the role of cell-to-cell adhesion heterogeneity. Scientific Reports, 8(1): p. 16200.
  40. Hayashi A., Giakoumakis N.N., Heidebrecht T., Ishii T., Panagopoulos A., Caillat C., Takahara M., Hibbert R.G., Suenaga N., Stadnik-Spiewak M., Takahashi T., Shiomi Y., Taraviras S., von Castelmur E., Lygerou Z., Perrakis A., Nishitani H. (2018)  Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2 E3 ligase activity to Cdt1.  Life Sci Alliance, 1(6): e201800238.